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Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction

BACKGROUND: Eyelid retraction is the most common and often the first sign of thyroid eye disease (TED). Upper-eyelid retraction causes both functional and cosmetic problems. In order to correct the position of the upper eyelid, surgery is required. Many procedures have demonstrated good outcomes in...

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Autores principales: Sun, Jing, Liu, Xingtong, Zhang, Yidan, Huang, Yazhuo, Zhong, Sisi, Fang, Sijie, Zhuang, Ai, Li, Yinwei, Zhou, Huifang, Fan, Xianqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952806/
https://www.ncbi.nlm.nih.gov/pubmed/29718902
http://dx.doi.org/10.12659/MSM.909306
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author Sun, Jing
Liu, Xingtong
Zhang, Yidan
Huang, Yazhuo
Zhong, Sisi
Fang, Sijie
Zhuang, Ai
Li, Yinwei
Zhou, Huifang
Fan, Xianqun
author_facet Sun, Jing
Liu, Xingtong
Zhang, Yidan
Huang, Yazhuo
Zhong, Sisi
Fang, Sijie
Zhuang, Ai
Li, Yinwei
Zhou, Huifang
Fan, Xianqun
author_sort Sun, Jing
collection PubMed
description BACKGROUND: Eyelid retraction is the most common and often the first sign of thyroid eye disease (TED). Upper-eyelid retraction causes both functional and cosmetic problems. In order to correct the position of the upper eyelid, surgery is required. Many procedures have demonstrated good outcomes in mild and moderate cases; however, unpredictable results have been obtained in severe cases. Dryden introduced an upper-eyelid-lengthening procedure, which used scleral grafts, but outcomes were unsatisfactory. A new technique is introduced in this study as a reasonable alternative for TED-related severe upper-eyelid retraction correction. MATERIAL/METHODS: An innovative technique for levator lengthening using bovine acellular dermal matrix as a spacer graft is introduced for severe upper-eyelid retraction secondary to TED. Additionally, 2 modifications were introduced: the fibrous cords scattered on the surface of the levator aponeurosis were excised and the orbital fat pad anterior to the aponeurosis was dissected and sutured into the skin closure in a “skin-tarsus-fat-skin” fashion. RESULTS: The modified levator-lengthening surgery was performed on 32 eyelids in 26 patients consisting of 21 women and 5 men (mean age, 37.8 years; age range, 19–67 years). After corrective surgery, the average upper margin reflex distance was lowered from 7.7±0.85 mm to 3.3±0.43 mm. Eighteen cases (69%) had perfect results, while 6 cases (23%) had acceptable results. CONCLUSIONS: A modified levator-lengthening procedure using bovine acellular dermal matrix as a spacer graft ameliorated both the symptoms and signs of severe upper-eyelid retraction secondary to TED. This procedure is a reasonable alternative for correction of TED-related severe upper-eyelid retraction.
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spelling pubmed-59528062018-05-17 Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction Sun, Jing Liu, Xingtong Zhang, Yidan Huang, Yazhuo Zhong, Sisi Fang, Sijie Zhuang, Ai Li, Yinwei Zhou, Huifang Fan, Xianqun Med Sci Monit Clinical Research BACKGROUND: Eyelid retraction is the most common and often the first sign of thyroid eye disease (TED). Upper-eyelid retraction causes both functional and cosmetic problems. In order to correct the position of the upper eyelid, surgery is required. Many procedures have demonstrated good outcomes in mild and moderate cases; however, unpredictable results have been obtained in severe cases. Dryden introduced an upper-eyelid-lengthening procedure, which used scleral grafts, but outcomes were unsatisfactory. A new technique is introduced in this study as a reasonable alternative for TED-related severe upper-eyelid retraction correction. MATERIAL/METHODS: An innovative technique for levator lengthening using bovine acellular dermal matrix as a spacer graft is introduced for severe upper-eyelid retraction secondary to TED. Additionally, 2 modifications were introduced: the fibrous cords scattered on the surface of the levator aponeurosis were excised and the orbital fat pad anterior to the aponeurosis was dissected and sutured into the skin closure in a “skin-tarsus-fat-skin” fashion. RESULTS: The modified levator-lengthening surgery was performed on 32 eyelids in 26 patients consisting of 21 women and 5 men (mean age, 37.8 years; age range, 19–67 years). After corrective surgery, the average upper margin reflex distance was lowered from 7.7±0.85 mm to 3.3±0.43 mm. Eighteen cases (69%) had perfect results, while 6 cases (23%) had acceptable results. CONCLUSIONS: A modified levator-lengthening procedure using bovine acellular dermal matrix as a spacer graft ameliorated both the symptoms and signs of severe upper-eyelid retraction secondary to TED. This procedure is a reasonable alternative for correction of TED-related severe upper-eyelid retraction. International Scientific Literature, Inc. 2018-05-02 /pmc/articles/PMC5952806/ /pubmed/29718902 http://dx.doi.org/10.12659/MSM.909306 Text en © Med Sci Monit, 2018 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Sun, Jing
Liu, Xingtong
Zhang, Yidan
Huang, Yazhuo
Zhong, Sisi
Fang, Sijie
Zhuang, Ai
Li, Yinwei
Zhou, Huifang
Fan, Xianqun
Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction
title Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction
title_full Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction
title_fullStr Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction
title_full_unstemmed Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction
title_short Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction
title_sort bovine acellular dermal matrix for levator lengthening in thyroid-related upper-eyelid retraction
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952806/
https://www.ncbi.nlm.nih.gov/pubmed/29718902
http://dx.doi.org/10.12659/MSM.909306
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