Direct measurement of pervasive weak repression by microRNAs and their role at the network level

BACKGROUND: A gene regulatory network (GRN) comprises many weak links that are often regulated by microRNAs. Since miRNAs rarely repress their target genes by more than 30%, doubts have been expressed about the biological relevance of such weak effects. These doubts raise the possibility of under-es...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Fuqiang, Lin, Pei, Chen, Qingjian, Lu, Xuemei, Zhang, Yong E., Wu, Chung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952853/
https://www.ncbi.nlm.nih.gov/pubmed/29764374
http://dx.doi.org/10.1186/s12864-018-4757-z

Ejemplares similares

Ejemplares similares