Uric acid disrupts hypochlorous acid production and the bactericidal activity of HL-60 cells

Uric acid is the end product of purine metabolism in humans and is an alternative physiological substrate for myeloperoxidase. Oxidation of uric acid by this enzyme generates uric acid free radical and urate hydroperoxide, a strong oxidant and potentially bactericide agent. In this study, we investi...

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Detalles Bibliográficos
Autores principales: Carvalho, Larissa A.C., Lopes, João P.P.B., Kaihami, Gilberto H., Silva, Railmara P., Bruni-Cardoso, Alexandre, Baldini, Regina L., Meotti, Flavia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952876/
https://www.ncbi.nlm.nih.gov/pubmed/29510342
http://dx.doi.org/10.1016/j.redox.2018.02.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952876/
https://www.ncbi.nlm.nih.gov/pubmed/29510342
http://dx.doi.org/10.1016/j.redox.2018.02.020

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