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Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin
The endonuclease G gene (Endog), which codes for a mitochondrial nuclease, was identified as a determinant of cardiac hypertrophy. How ENDOG controls cardiomyocyte growth is still unknown. Thus, we aimed at finding the link between ENDOG activity and cardiomyocyte growth. Endog deficiency induced re...
Autores principales: | Blasco, Natividad, Cámara, Yolanda, Núñez, Estefanía, Beà, Aida, Barés, Gisel, Forné, Carles, Ruíz-Meana, Marisol, Girón, Cristina, Barba, Ignasi, García-Arumí, Elena, García-Dorado, David, Vázquez, Jesús, Martí, Ramon, Llovera, Marta, Sanchis, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952880/ https://www.ncbi.nlm.nih.gov/pubmed/29502044 http://dx.doi.org/10.1016/j.redox.2018.02.021 |
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