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Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis

INTRODUCTION: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORT: We report a case of Merkel’s abdominal carcinomas treated with extensive inguinal lympha...

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Detalles Bibliográficos
Autores principales: Coppola Bottazzi, Enrico, Noviello, Adele, Moles, Nicola, Miro, Antonio, Striano, Augusto, Baiamonte, Mario, Esposito, Francesco, Crafa, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952917/
https://www.ncbi.nlm.nih.gov/pubmed/29780576
http://dx.doi.org/10.1093/jscr/rjy098
Descripción
Sumario:INTRODUCTION: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORT: We report a case of Merkel’s abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE(®) BIO-A(®). DISCUSSION: Immunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin. MCC is an aggressive tumor with poor prognosis. CONCLUSIONS: For primary tumors without indications of the presence of organ metastases complete surgical excision is the gold standard. Gore BIO-A is a biosynthetic prosthesis with manageable structure that allows it to be positioned and shaped according to needs, its strength provides for excellent support for the reconstruction of the inguinal canal wall.