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Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis

INTRODUCTION: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORT: We report a case of Merkel’s abdominal carcinomas treated with extensive inguinal lympha...

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Autores principales: Coppola Bottazzi, Enrico, Noviello, Adele, Moles, Nicola, Miro, Antonio, Striano, Augusto, Baiamonte, Mario, Esposito, Francesco, Crafa, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952917/
https://www.ncbi.nlm.nih.gov/pubmed/29780576
http://dx.doi.org/10.1093/jscr/rjy098
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author Coppola Bottazzi, Enrico
Noviello, Adele
Moles, Nicola
Miro, Antonio
Striano, Augusto
Baiamonte, Mario
Esposito, Francesco
Crafa, Francesco
author_facet Coppola Bottazzi, Enrico
Noviello, Adele
Moles, Nicola
Miro, Antonio
Striano, Augusto
Baiamonte, Mario
Esposito, Francesco
Crafa, Francesco
author_sort Coppola Bottazzi, Enrico
collection PubMed
description INTRODUCTION: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORT: We report a case of Merkel’s abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE(®) BIO-A(®). DISCUSSION: Immunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin. MCC is an aggressive tumor with poor prognosis. CONCLUSIONS: For primary tumors without indications of the presence of organ metastases complete surgical excision is the gold standard. Gore BIO-A is a biosynthetic prosthesis with manageable structure that allows it to be positioned and shaped according to needs, its strength provides for excellent support for the reconstruction of the inguinal canal wall.
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spelling pubmed-59529172018-05-18 Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis Coppola Bottazzi, Enrico Noviello, Adele Moles, Nicola Miro, Antonio Striano, Augusto Baiamonte, Mario Esposito, Francesco Crafa, Francesco J Surg Case Rep Innovation INTRODUCTION: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORT: We report a case of Merkel’s abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE(®) BIO-A(®). DISCUSSION: Immunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin. MCC is an aggressive tumor with poor prognosis. CONCLUSIONS: For primary tumors without indications of the presence of organ metastases complete surgical excision is the gold standard. Gore BIO-A is a biosynthetic prosthesis with manageable structure that allows it to be positioned and shaped according to needs, its strength provides for excellent support for the reconstruction of the inguinal canal wall. Oxford University Press 2018-05-15 /pmc/articles/PMC5952917/ /pubmed/29780576 http://dx.doi.org/10.1093/jscr/rjy098 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Innovation
Coppola Bottazzi, Enrico
Noviello, Adele
Moles, Nicola
Miro, Antonio
Striano, Augusto
Baiamonte, Mario
Esposito, Francesco
Crafa, Francesco
Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
title Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
title_full Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
title_fullStr Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
title_full_unstemmed Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
title_short Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
title_sort merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
topic Innovation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952917/
https://www.ncbi.nlm.nih.gov/pubmed/29780576
http://dx.doi.org/10.1093/jscr/rjy098
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