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Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
INTRODUCTION: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORT: We report a case of Merkel’s abdominal carcinomas treated with extensive inguinal lympha...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952917/ https://www.ncbi.nlm.nih.gov/pubmed/29780576 http://dx.doi.org/10.1093/jscr/rjy098 |
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author | Coppola Bottazzi, Enrico Noviello, Adele Moles, Nicola Miro, Antonio Striano, Augusto Baiamonte, Mario Esposito, Francesco Crafa, Francesco |
author_facet | Coppola Bottazzi, Enrico Noviello, Adele Moles, Nicola Miro, Antonio Striano, Augusto Baiamonte, Mario Esposito, Francesco Crafa, Francesco |
author_sort | Coppola Bottazzi, Enrico |
collection | PubMed |
description | INTRODUCTION: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORT: We report a case of Merkel’s abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE(®) BIO-A(®). DISCUSSION: Immunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin. MCC is an aggressive tumor with poor prognosis. CONCLUSIONS: For primary tumors without indications of the presence of organ metastases complete surgical excision is the gold standard. Gore BIO-A is a biosynthetic prosthesis with manageable structure that allows it to be positioned and shaped according to needs, its strength provides for excellent support for the reconstruction of the inguinal canal wall. |
format | Online Article Text |
id | pubmed-5952917 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-59529172018-05-18 Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis Coppola Bottazzi, Enrico Noviello, Adele Moles, Nicola Miro, Antonio Striano, Augusto Baiamonte, Mario Esposito, Francesco Crafa, Francesco J Surg Case Rep Innovation INTRODUCTION: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORT: We report a case of Merkel’s abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE(®) BIO-A(®). DISCUSSION: Immunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin. MCC is an aggressive tumor with poor prognosis. CONCLUSIONS: For primary tumors without indications of the presence of organ metastases complete surgical excision is the gold standard. Gore BIO-A is a biosynthetic prosthesis with manageable structure that allows it to be positioned and shaped according to needs, its strength provides for excellent support for the reconstruction of the inguinal canal wall. Oxford University Press 2018-05-15 /pmc/articles/PMC5952917/ /pubmed/29780576 http://dx.doi.org/10.1093/jscr/rjy098 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Innovation Coppola Bottazzi, Enrico Noviello, Adele Moles, Nicola Miro, Antonio Striano, Augusto Baiamonte, Mario Esposito, Francesco Crafa, Francesco Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis |
title | Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis |
title_full | Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis |
title_fullStr | Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis |
title_full_unstemmed | Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis |
title_short | Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis |
title_sort | merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis |
topic | Innovation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952917/ https://www.ncbi.nlm.nih.gov/pubmed/29780576 http://dx.doi.org/10.1093/jscr/rjy098 |
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