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MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1

OBJECTIVE: Several miR/s that regulate gene/s relevant in atherogenesis are being described. We identified a miR (miR-98) that targets LOX-1, a receptor for ox-LDL, and speculated that it might be relevant in atherogenesis. APPROACH AND RESULTS: MicroRNA-98 was predicted by bioinformatics tools. The...

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Detalles Bibliográficos
Autores principales:	Dai, Yao, Wu, Xiaoqin, Dai, Dongsheng, Li, Jun, Mehta, Jawahar L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952997/ https://www.ncbi.nlm.nih.gov/pubmed/29549823 http://dx.doi.org/10.1016/j.redox.2018.03.003

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