Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity

Classical activation of M1 macrophages with lipopolysaccharide (LPS) is associated with a metabolic switch from oxidative phosphorylation to glycolysis. However, the generalizability of such metabolic remodeling to other modes of M1 macrophage stimulation, e.g. type II interferons (IFNs) such as IFN...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Feilong, Zhang, Song, Jeon, Ryounghoon, Vuckovic, Ivan, Jiang, Xintong, Lerman, Amir, Folmes, Clifford D., Dzeja, Petras D., Herrmann, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953001/
https://www.ncbi.nlm.nih.gov/pubmed/29463472
http://dx.doi.org/10.1016/j.ebiom.2018.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953001/
https://www.ncbi.nlm.nih.gov/pubmed/29463472
http://dx.doi.org/10.1016/j.ebiom.2018.02.009

Ejemplares similares