Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity

Classical activation of M1 macrophages with lipopolysaccharide (LPS) is associated with a metabolic switch from oxidative phosphorylation to glycolysis. However, the generalizability of such metabolic remodeling to other modes of M1 macrophage stimulation, e.g. type II interferons (IFNs) such as IFN...

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Detalles Bibliográficos
Autores principales: Wang, Feilong, Zhang, Song, Jeon, Ryounghoon, Vuckovic, Ivan, Jiang, Xintong, Lerman, Amir, Folmes, Clifford D., Dzeja, Petras D., Herrmann, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953001/
https://www.ncbi.nlm.nih.gov/pubmed/29463472
http://dx.doi.org/10.1016/j.ebiom.2018.02.009

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