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Quetiapine Related Acute Paralytic Ileus in a Bipolar I Disorder Patient with Successful Low Dose Amisulpride Substitution: A Case Report

The mechanism of medication-induced gastrointestinal hypomotility is primarily caused by muscarinic cholinergic antagonism. This effect may cause constipation and paralytic ileus, which may lead to fatal complications. A 51-year-old woman was admitted due to manic episode recurrence. She developed p...

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Detalles Bibliográficos
Autores principales: Chiang, Shun-Ting, Lan, Chen-Chia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953026/
https://www.ncbi.nlm.nih.gov/pubmed/29739140
http://dx.doi.org/10.9758/cpn.2018.16.2.228
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author Chiang, Shun-Ting
Lan, Chen-Chia
author_facet Chiang, Shun-Ting
Lan, Chen-Chia
author_sort Chiang, Shun-Ting
collection PubMed
description The mechanism of medication-induced gastrointestinal hypomotility is primarily caused by muscarinic cholinergic antagonism. This effect may cause constipation and paralytic ileus, which may lead to fatal complications. A 51-year-old woman was admitted due to manic episode recurrence. She developed paralytic ileus under quetiapine use and treated successfully under low dose amisulpride use. The related mechanism, associated risk factors, and the rationale for medication switch are discussed.
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spelling pubmed-59530262018-05-18 Quetiapine Related Acute Paralytic Ileus in a Bipolar I Disorder Patient with Successful Low Dose Amisulpride Substitution: A Case Report Chiang, Shun-Ting Lan, Chen-Chia Clin Psychopharmacol Neurosci Case Report The mechanism of medication-induced gastrointestinal hypomotility is primarily caused by muscarinic cholinergic antagonism. This effect may cause constipation and paralytic ileus, which may lead to fatal complications. A 51-year-old woman was admitted due to manic episode recurrence. She developed paralytic ileus under quetiapine use and treated successfully under low dose amisulpride use. The related mechanism, associated risk factors, and the rationale for medication switch are discussed. Korean College of Neuropsychopharmacology 2018-05 2018-05-31 /pmc/articles/PMC5953026/ /pubmed/29739140 http://dx.doi.org/10.9758/cpn.2018.16.2.228 Text en Copyright © 2018, Korean College of Neuropsychopharmacology This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chiang, Shun-Ting
Lan, Chen-Chia
Quetiapine Related Acute Paralytic Ileus in a Bipolar I Disorder Patient with Successful Low Dose Amisulpride Substitution: A Case Report
title Quetiapine Related Acute Paralytic Ileus in a Bipolar I Disorder Patient with Successful Low Dose Amisulpride Substitution: A Case Report
title_full Quetiapine Related Acute Paralytic Ileus in a Bipolar I Disorder Patient with Successful Low Dose Amisulpride Substitution: A Case Report
title_fullStr Quetiapine Related Acute Paralytic Ileus in a Bipolar I Disorder Patient with Successful Low Dose Amisulpride Substitution: A Case Report
title_full_unstemmed Quetiapine Related Acute Paralytic Ileus in a Bipolar I Disorder Patient with Successful Low Dose Amisulpride Substitution: A Case Report
title_short Quetiapine Related Acute Paralytic Ileus in a Bipolar I Disorder Patient with Successful Low Dose Amisulpride Substitution: A Case Report
title_sort quetiapine related acute paralytic ileus in a bipolar i disorder patient with successful low dose amisulpride substitution: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953026/
https://www.ncbi.nlm.nih.gov/pubmed/29739140
http://dx.doi.org/10.9758/cpn.2018.16.2.228
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