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Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

Developmental synapse pruning refines burgeoning connectomes. The basic mechanisms of mitochondrial reactive oxygen species (ROS) production suggest they select inactive synapses for pruning: whether they do so is unknown. To begin to unravel whether mitochondrial ROS regulate pruning, we made the l...

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Detalles Bibliográficos
Autores principales:	Sidlauskaite, Eva, Gibson, Jack W., Megson, Ian L., Whitfield, Philip D., Tovmasyan, Artak, Batinic-Haberle, Ines, Murphy, Michael P., Moult, Peter R., Cobley, James N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953219/ https://www.ncbi.nlm.nih.gov/pubmed/29587245 http://dx.doi.org/10.1016/j.redox.2018.03.012

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