Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription

OBJECTIVE: Reduction of oxidized methionines is emerging as a major protein repair pathway. The lack of methionine sulfoxide reductase A (MsrA) exacerbates cardiovascular disease phenotypes driven by increased oxidative stress. However, the role of MsrA on maintaining cellular homeostasis in the abs...

Descripción completa

Detalles Bibliográficos
Autores principales: Pennington, Steven M., Klutho, Paula R., Xie, Litao, Broadhurst, Kim, Koval, Olha M., McCormick, Michael L., Spitz, Douglas R., Grumbach, Isabella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953240/
https://www.ncbi.nlm.nih.gov/pubmed/29649787
http://dx.doi.org/10.1016/j.redox.2018.04.001

Ejemplares similares

Ejemplares similares