Cargando…

Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways

INTRODUCTION: Osteoarthritis (OA) is the most prevalent joint disorder in the elderly population, and inflammatory mediators like IL-1β were thought to play central roles in its development. Schisandrin B, the main active component derived from Schisandra chinensis, exhibited anti-oxidative and anti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ran, Jisheng, Ma, Chiyuan, Xu, Kai, Xu, Langhai, He, Yuzhe, Moqbel, Safwat Adel Abdo, Hu, Pengfei, Jiang, Lifeng, Chen, Weiping, Bao, Jiapeng, Xiong, Yan, Wu, Lidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953308/ https://www.ncbi.nlm.nih.gov/pubmed/29785089 http://dx.doi.org/10.2147/DDDT.S162014

Ejemplares similares

Rat Chondrocyte Inflammation and Osteoarthritis Are Ameliorated by Madecassoside
por: Moqbel, Safwat Adel Abdo, et al.
Publicado: (2020)

Costunolide inhibits matrix metalloproteinases expression and osteoarthritis via the NF-κB and Wnt/β-catenin signaling pathways
por: He, Yuzhe, et al.
Publicado: (2019)

Reactivation of NR4A1 Restrains Chondrocyte Inflammation and Ameliorates Osteoarthritis in Rats
por: Xiong, Yan, et al.
Publicado: (2020)

DUSP5 suppresses interleukin-1β-induced chondrocyte inflammation and ameliorates osteoarthritis in rats
por: Wu, Zhipeng, et al.
Publicado: (2020)

Tectorigenin Alleviates Inflammation, Apoptosis, and Ossification in Rat Tendon-Derived Stem Cells via Modulating NF-Kappa B and MAPK Pathways
por: Moqbel, Safwat Adel Abdo, et al.
Publicado: (2020)

circFAM160A2 Promotes Mitochondrial Stabilization and Apoptosis Reduction in Osteoarthritis Chondrocytes by Targeting miR-505-3p and SIRT3
por: Bao, Jiapeng, et al.
Publicado: (2021)

Laser Acupuncture for Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials
por: Chen, Zhonggai, et al.
Publicado: (2019)

The effect of mitochondrial fusion on chondrogenic differentiation of cartilage progenitor/stem cells via Notch2 signal pathway
por: Moqbel, Safwat Adel Abdo, et al.
Publicado: (2022)

Spironolactone Ameliorates Senescence and Calcification by Modulating Autophagy in Rat Tendon-Derived Stem Cells via the NF-κB/MAPK Pathway
por: Xu, Kai, et al.
Publicado: (2021)

Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats
por: Jiang, Lifeng, et al.
Publicado: (2020)

Tectorigenin inhibits RANKL‐induced osteoclastogenesis via suppression of NF‐κB signalling and decreases bone loss in ovariectomized C57BL/6
por: Ma, Chiyuan, et al.
Publicado: (2018)

The pro‐inflammatory effect of NR4A3 in osteoarthritis
por: Ma, Chiyuan, et al.
Publicado: (2019)

Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway
por: Jiang, Lifeng, et al.
Publicado: (2023)

Pioglitazone attenuates advanced glycation end products‐induced apoptosis and calcification by modulating autophagy in tendon‐derived stem cells
por: Xu, Langhai, et al.
Publicado: (2020)

Nesfatin-1 Promotes the Osteogenic Differentiation of Tendon-Derived Stem Cells and the Pathogenesis of Heterotopic Ossification in Rat Tendons via the mTOR Pathway
por: Xu, Kai, et al.
Publicado: (2020)

Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROS
por: Lin, Changjian, et al.
Publicado: (2022)

Rapamycin protects chondrocytes against IL-18-induced apoptosis and ameliorates rat osteoarthritis
por: Bao, Jiapeng, et al.
Publicado: (2020)

Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes
por: Bao, Jiapeng, et al.
Publicado: (2017)

Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes
por: Tu, Chang, et al.
Publicado: (2019)

Schisandrin B for the treatment of male infertility
por: Zou, Di‐Xin, et al.
Publicado: (2021)

Increased Serum Levels and Chondrocyte Expression of Nesfatin-1 in Patients with Osteoarthritis and Its Relation with BMI, hsCRP, and IL-18
por: Jiang, Lifeng, et al.
Publicado: (2013)

Oleanolic Acid Decreases IL-1β-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-κB Axis in Osteoarthritis
por: Bao, Jiapeng, et al.
Publicado: (2020)

Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway
por: Yao, Minjun, et al.
Publicado: (2022)

Schisandrin B attenuates pressure overload-induced cardiac remodeling in mice by inhibiting the MAPK signaling pathway
por: Ai, Fen, et al.
Publicado: (2019)

Wnt/β-catenin signaling may induce senescence of chondrocytes in osteoarthritis
por: Li, Weijun, et al.
Publicado: (2020)

Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes
por: Zhou, Feng, et al.
Publicado: (2019)

Schisandrin B Prevents Hind Limb from Ischemia-Reperfusion-Induced Oxidative Stress and Inflammation via MAPK/NF-κB Pathways in Rats
por: Zhu, Ning, et al.
Publicado: (2017)

Schisandrin B regulates lipid metabolism in subcutaneous adipocytes
por: Kwan, Hiu Yee, et al.
Publicado: (2017)

Specnuezhenide Decreases Interleukin-1β-Induced Inflammation in Rat Chondrocytes and Reduces Joint Destruction in Osteoarthritic Rats
por: Ma, Chiyuan, et al.
Publicado: (2018)

Ononin ameliorates inflammation and cartilage degradation in rat chondrocytes with IL-1β-induced osteoarthritis by downregulating the MAPK and NF-κB pathways
por: Xu, Fang, et al.
Publicado: (2022)

A Comprehensive Review on Schisandrin B and Its Biological Properties
por: Nasser, M. I., et al.
Publicado: (2020)

Beneficial Effects of Schisandrin B on the Cardiac Function in Mice Model of Myocardial Infarction
por: Chen, Pengsheng, et al.
Publicado: (2013)

Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response
por: Leong, Pou Kuan, et al.
Publicado: (2016)

Schisandrin B Induces Apoptosis and Cell Cycle Arrest of Gallbladder Cancer Cells
por: Xiang, Shan-Shan, et al.
Publicado: (2014)

miR-7/EGFR/MEGF9 axis regulates cartilage degradation in osteoarthritis via PI3K/AKT/mTOR signaling pathway
por: Jiang, Lifeng, et al.
Publicado: (2021)

The efficacy and molecular mechanism of the effect of schisandrin b on the treatment of erectile dysfunction
por: Liu, Wei, et al.
Publicado: (2019)

Prevention of the Pro-Aggressive Effects of Ethanol-Intoxicated Mice by Schisandrin B
por: Lam, Ho Yin Pekkle, et al.
Publicado: (2023)

Association between interleukin-17A/F single nucleotide polymorphisms and susceptibility to osteoarthritis in a Chinese population
por: Jiang, Lifeng, et al.
Publicado: (2019)

Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages
por: Jin, Yu, et al.
Publicado: (2022)

Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression
por: Giridharan, Vijayasree V., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_eqc175ugd8nafbrb5utgotuq0j