Cargando…

Enhancement of Astroglial Aerobic Glycolysis by Extracellular Lactate-Mediated Increase in cAMP

Besides being a neuronal fuel, L-lactate is also a signal in the brain. Whether extracellular L-lactate affects brain metabolism, in particular astrocytes, abundant neuroglial cells, which produce L-lactate in aerobic glycolysis, is unclear. Recent studies suggested that astrocytes express low level...

Descripción completa

Detalles Bibliográficos
Autores principales: Vardjan, Nina, Chowdhury, Helena H., Horvat, Anemari, Velebit, Jelena, Malnar, Maja, Muhič, Marko, Kreft, Marko, Krivec, Špela G., Bobnar, Saša T., Miš, Katarina, Pirkmajer, Sergej, Offermanns, Stefan, Henriksen, Gjermund, Storm-Mathisen, Jon, Bergersen, Linda H., Zorec, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953330/
https://www.ncbi.nlm.nih.gov/pubmed/29867342
http://dx.doi.org/10.3389/fnmol.2018.00148