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Enhancement of Astroglial Aerobic Glycolysis by Extracellular Lactate-Mediated Increase in cAMP
Besides being a neuronal fuel, L-lactate is also a signal in the brain. Whether extracellular L-lactate affects brain metabolism, in particular astrocytes, abundant neuroglial cells, which produce L-lactate in aerobic glycolysis, is unclear. Recent studies suggested that astrocytes express low level...
Autores principales: | Vardjan, Nina, Chowdhury, Helena H., Horvat, Anemari, Velebit, Jelena, Malnar, Maja, Muhič, Marko, Kreft, Marko, Krivec, Špela G., Bobnar, Saša T., Miš, Katarina, Pirkmajer, Sergej, Offermanns, Stefan, Henriksen, Gjermund, Storm-Mathisen, Jon, Bergersen, Linda H., Zorec, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953330/ https://www.ncbi.nlm.nih.gov/pubmed/29867342 http://dx.doi.org/10.3389/fnmol.2018.00148 |
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