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The influence of spinal-pelvic parameters on the prevalence of endplate Modic changes in degenerative thoracolumbar/lumbar kyphosis patients

BACKGROUND: The typical degeneration of the vertebral endplate shown in MRI imaging is Modic change. The aim of this study was to observe the distribution of the Modic changes of vertebral endplate in degenerative thoracolumbar/lumbar kyphosis (DTK/LK) patients and analyse the correlation between sp...

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Autores principales: Xia, Weiwei, Liu, Chenjun, Duan, Shuo, Xu, Shuai, Wang, Kaifeng, Zhu, Zhenqi, Liu, Haiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953463/
https://www.ncbi.nlm.nih.gov/pubmed/29763470
http://dx.doi.org/10.1371/journal.pone.0197470
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author Xia, Weiwei
Liu, Chenjun
Duan, Shuo
Xu, Shuai
Wang, Kaifeng
Zhu, Zhenqi
Liu, Haiying
author_facet Xia, Weiwei
Liu, Chenjun
Duan, Shuo
Xu, Shuai
Wang, Kaifeng
Zhu, Zhenqi
Liu, Haiying
author_sort Xia, Weiwei
collection PubMed
description BACKGROUND: The typical degeneration of the vertebral endplate shown in MRI imaging is Modic change. The aim of this study was to observe the distribution of the Modic changes of vertebral endplate in degenerative thoracolumbar/lumbar kyphosis (DTK/LK) patients and analyse the correlation between spinal-pelvic parameters and Modic changes. METHODS: The imaging data of 58 patients diagnosed with DTK/LK (coronal Cobb angle<10°with sagittal imbalance) in our hospital from March 2016 to May 2017 were reviewed retrospectively. Observe the prevalence, type and distribution characteristics of Modic changes occurred at the vertebral endplate from T10 to S1;analyse the correlation between Modic changes and disc degeneration, the sagittal vertical axis (SVA), thoracic kyphosis (TK), thoracolumbar kyphosis (TLK), lumbar lordosis (LL), sacral slope (SS), pelvic tilt (PT) and pelvic incidence (PI). RESULTS: Of the 928 intervertebral endplates from 58 patients, Modic changes occurred at 90 endplates (9.7%) of 30 patients (51.7%). 5 endplates (0.5%) of 3 patients (5.2%) were classified as type I, 68 endplates (7.3%) of 25 patients (43.1%) as type II, 17 endplates (1.8%) of 9 patients (15.5%) as type III. The location of the degenerative endplates: 2 (2.2%) superior and inferior endplates of L1, 3 (3.3%) inferior endplates of T11and T12, 4 (4.4%) superior endplates of L2, 6 (6.7%) inferior endplates of L2 and L4, 8 (8.9%) superior endplates of S1, 9 (10%) superior endplates of L3, 11 (12.2%) inferior endplates of L3 and L5 and superior endplates of L4, 12 (13.3%) superior endplates of L5. Modic changes were significantly correlated with intervertebral disc degeneration (r = 0.414, p<0.01); the amount of Modic changes were significantly correlated with LL (r = -0.562, p = 0.012), SS (r = -0.46, p = 0.048), PT (r = 0.516, p = 0.024). CONCLUSIONS: Most of the Modic changes of vertebral endplates in DTK/LK patients are type II which are prevalently located at L3/4, L4/5 and L5/S1. The Modic changes of vertebral endplates were found to be significantly correlated with disc degeneration, LL, SS, and PT.
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spelling pubmed-59534632018-05-25 The influence of spinal-pelvic parameters on the prevalence of endplate Modic changes in degenerative thoracolumbar/lumbar kyphosis patients Xia, Weiwei Liu, Chenjun Duan, Shuo Xu, Shuai Wang, Kaifeng Zhu, Zhenqi Liu, Haiying PLoS One Research Article BACKGROUND: The typical degeneration of the vertebral endplate shown in MRI imaging is Modic change. The aim of this study was to observe the distribution of the Modic changes of vertebral endplate in degenerative thoracolumbar/lumbar kyphosis (DTK/LK) patients and analyse the correlation between spinal-pelvic parameters and Modic changes. METHODS: The imaging data of 58 patients diagnosed with DTK/LK (coronal Cobb angle<10°with sagittal imbalance) in our hospital from March 2016 to May 2017 were reviewed retrospectively. Observe the prevalence, type and distribution characteristics of Modic changes occurred at the vertebral endplate from T10 to S1;analyse the correlation between Modic changes and disc degeneration, the sagittal vertical axis (SVA), thoracic kyphosis (TK), thoracolumbar kyphosis (TLK), lumbar lordosis (LL), sacral slope (SS), pelvic tilt (PT) and pelvic incidence (PI). RESULTS: Of the 928 intervertebral endplates from 58 patients, Modic changes occurred at 90 endplates (9.7%) of 30 patients (51.7%). 5 endplates (0.5%) of 3 patients (5.2%) were classified as type I, 68 endplates (7.3%) of 25 patients (43.1%) as type II, 17 endplates (1.8%) of 9 patients (15.5%) as type III. The location of the degenerative endplates: 2 (2.2%) superior and inferior endplates of L1, 3 (3.3%) inferior endplates of T11and T12, 4 (4.4%) superior endplates of L2, 6 (6.7%) inferior endplates of L2 and L4, 8 (8.9%) superior endplates of S1, 9 (10%) superior endplates of L3, 11 (12.2%) inferior endplates of L3 and L5 and superior endplates of L4, 12 (13.3%) superior endplates of L5. Modic changes were significantly correlated with intervertebral disc degeneration (r = 0.414, p<0.01); the amount of Modic changes were significantly correlated with LL (r = -0.562, p = 0.012), SS (r = -0.46, p = 0.048), PT (r = 0.516, p = 0.024). CONCLUSIONS: Most of the Modic changes of vertebral endplates in DTK/LK patients are type II which are prevalently located at L3/4, L4/5 and L5/S1. The Modic changes of vertebral endplates were found to be significantly correlated with disc degeneration, LL, SS, and PT. Public Library of Science 2018-05-15 /pmc/articles/PMC5953463/ /pubmed/29763470 http://dx.doi.org/10.1371/journal.pone.0197470 Text en © 2018 Xia et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Xia, Weiwei
Liu, Chenjun
Duan, Shuo
Xu, Shuai
Wang, Kaifeng
Zhu, Zhenqi
Liu, Haiying
The influence of spinal-pelvic parameters on the prevalence of endplate Modic changes in degenerative thoracolumbar/lumbar kyphosis patients
title The influence of spinal-pelvic parameters on the prevalence of endplate Modic changes in degenerative thoracolumbar/lumbar kyphosis patients
title_full The influence of spinal-pelvic parameters on the prevalence of endplate Modic changes in degenerative thoracolumbar/lumbar kyphosis patients
title_fullStr The influence of spinal-pelvic parameters on the prevalence of endplate Modic changes in degenerative thoracolumbar/lumbar kyphosis patients
title_full_unstemmed The influence of spinal-pelvic parameters on the prevalence of endplate Modic changes in degenerative thoracolumbar/lumbar kyphosis patients
title_short The influence of spinal-pelvic parameters on the prevalence of endplate Modic changes in degenerative thoracolumbar/lumbar kyphosis patients
title_sort influence of spinal-pelvic parameters on the prevalence of endplate modic changes in degenerative thoracolumbar/lumbar kyphosis patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953463/
https://www.ncbi.nlm.nih.gov/pubmed/29763470
http://dx.doi.org/10.1371/journal.pone.0197470
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