Natural disease history of the dy(2J) mouse model of laminin α2 (merosin)-deficient congenital muscular dystrophy

Merosin deficient congenital muscular dystrophy 1A (MDC1A) is a very rare autosomal recessive disorder caused by mutations in the LAMA2 gene leading to severe and progressive muscle weakness and atrophy. Although over 350 causative mutations have been identified for MDC1A, no treatment is yet availa...

Descripción completa

Detalles Bibliográficos
Autores principales: Pasteuning-Vuhman, S., Putker, K., Tanganyika-de Winter, C. L., Boertje-van der Meulen, J. W., van Vliet, L., Overzier, M., Plomp, J. J., Aartsma-Rus, A., van Putten, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953480/
https://www.ncbi.nlm.nih.gov/pubmed/29763467
http://dx.doi.org/10.1371/journal.pone.0197388

Ejemplares similares

Ejemplares similares