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Prion protein protects mice from lethal infection with influenza A viruses
The cellular prion protein, designated PrP(C), is a membrane glycoprotein expressed abundantly in brains and to a lesser extent in other tissues. Conformational conversion of PrP(C) into the amyloidogenic isoform is a key pathogenic event in prion diseases. However, the physiological functions of Pr...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953499/ https://www.ncbi.nlm.nih.gov/pubmed/29723291 http://dx.doi.org/10.1371/journal.ppat.1007049 |