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Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report

Amyloidosis is a rare disease, which can affect various organs, such as the kidneys, heart, liver, respiratory and gastrointestinal tracts, and the nervous system. It still has a bad prognosis nowadays, despite chemotherapy and the new biotherapies. Its physiopathology corresponds to an irreversible...

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Detalles Bibliográficos
Autores principales: El Issa, Meidi, El Issa, Malik, Sidia, Besma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953506/
https://www.ncbi.nlm.nih.gov/pubmed/29770283
http://dx.doi.org/10.7759/cureus.2330
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author El Issa, Meidi
El Issa, Malik
Sidia, Besma
author_facet El Issa, Meidi
El Issa, Malik
Sidia, Besma
author_sort El Issa, Meidi
collection PubMed
description Amyloidosis is a rare disease, which can affect various organs, such as the kidneys, heart, liver, respiratory and gastrointestinal tracts, and the nervous system. It still has a bad prognosis nowadays, despite chemotherapy and the new biotherapies. Its physiopathology corresponds to an irreversible, extracellular accumulation of fibrillous proteins in the tissues. Notwithstanding the fact that a clear diagnosis can be made with histology (of solid injured organs or a subcutaneous biopsy), magnetic resonance imaging (MRI) can show various advantages, especially to prove cardiac involvement, with great specificity and sensibility as well. Consequently, the MRI's place can be considered a cornerstone of the diagnosis; more so because biopsies are not routine and easy procedures. Moreover, amyloidosis includes several symptoms, which are sometimes tricky, so the clinician should swiftly consider the usefulness of MRI to get the patient well-oriented and treated.
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spelling pubmed-59535062018-05-16 Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report El Issa, Meidi El Issa, Malik Sidia, Besma Cureus Cardiology Amyloidosis is a rare disease, which can affect various organs, such as the kidneys, heart, liver, respiratory and gastrointestinal tracts, and the nervous system. It still has a bad prognosis nowadays, despite chemotherapy and the new biotherapies. Its physiopathology corresponds to an irreversible, extracellular accumulation of fibrillous proteins in the tissues. Notwithstanding the fact that a clear diagnosis can be made with histology (of solid injured organs or a subcutaneous biopsy), magnetic resonance imaging (MRI) can show various advantages, especially to prove cardiac involvement, with great specificity and sensibility as well. Consequently, the MRI's place can be considered a cornerstone of the diagnosis; more so because biopsies are not routine and easy procedures. Moreover, amyloidosis includes several symptoms, which are sometimes tricky, so the clinician should swiftly consider the usefulness of MRI to get the patient well-oriented and treated. Cureus 2018-03-15 /pmc/articles/PMC5953506/ /pubmed/29770283 http://dx.doi.org/10.7759/cureus.2330 Text en Copyright © 2018, El Issa et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
El Issa, Meidi
El Issa, Malik
Sidia, Besma
Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report
title Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report
title_full Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report
title_fullStr Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report
title_full_unstemmed Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report
title_short Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report
title_sort cardiac amyloidosis diagnosis with magnetic resonance imaging: a case report
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953506/
https://www.ncbi.nlm.nih.gov/pubmed/29770283
http://dx.doi.org/10.7759/cureus.2330
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