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Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report
Amyloidosis is a rare disease, which can affect various organs, such as the kidneys, heart, liver, respiratory and gastrointestinal tracts, and the nervous system. It still has a bad prognosis nowadays, despite chemotherapy and the new biotherapies. Its physiopathology corresponds to an irreversible...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953506/ https://www.ncbi.nlm.nih.gov/pubmed/29770283 http://dx.doi.org/10.7759/cureus.2330 |
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author | El Issa, Meidi El Issa, Malik Sidia, Besma |
author_facet | El Issa, Meidi El Issa, Malik Sidia, Besma |
author_sort | El Issa, Meidi |
collection | PubMed |
description | Amyloidosis is a rare disease, which can affect various organs, such as the kidneys, heart, liver, respiratory and gastrointestinal tracts, and the nervous system. It still has a bad prognosis nowadays, despite chemotherapy and the new biotherapies. Its physiopathology corresponds to an irreversible, extracellular accumulation of fibrillous proteins in the tissues. Notwithstanding the fact that a clear diagnosis can be made with histology (of solid injured organs or a subcutaneous biopsy), magnetic resonance imaging (MRI) can show various advantages, especially to prove cardiac involvement, with great specificity and sensibility as well. Consequently, the MRI's place can be considered a cornerstone of the diagnosis; more so because biopsies are not routine and easy procedures. Moreover, amyloidosis includes several symptoms, which are sometimes tricky, so the clinician should swiftly consider the usefulness of MRI to get the patient well-oriented and treated. |
format | Online Article Text |
id | pubmed-5953506 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-59535062018-05-16 Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report El Issa, Meidi El Issa, Malik Sidia, Besma Cureus Cardiology Amyloidosis is a rare disease, which can affect various organs, such as the kidneys, heart, liver, respiratory and gastrointestinal tracts, and the nervous system. It still has a bad prognosis nowadays, despite chemotherapy and the new biotherapies. Its physiopathology corresponds to an irreversible, extracellular accumulation of fibrillous proteins in the tissues. Notwithstanding the fact that a clear diagnosis can be made with histology (of solid injured organs or a subcutaneous biopsy), magnetic resonance imaging (MRI) can show various advantages, especially to prove cardiac involvement, with great specificity and sensibility as well. Consequently, the MRI's place can be considered a cornerstone of the diagnosis; more so because biopsies are not routine and easy procedures. Moreover, amyloidosis includes several symptoms, which are sometimes tricky, so the clinician should swiftly consider the usefulness of MRI to get the patient well-oriented and treated. Cureus 2018-03-15 /pmc/articles/PMC5953506/ /pubmed/29770283 http://dx.doi.org/10.7759/cureus.2330 Text en Copyright © 2018, El Issa et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology El Issa, Meidi El Issa, Malik Sidia, Besma Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report |
title | Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report |
title_full | Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report |
title_fullStr | Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report |
title_full_unstemmed | Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report |
title_short | Cardiac Amyloidosis Diagnosis with Magnetic Resonance Imaging: A Case Report |
title_sort | cardiac amyloidosis diagnosis with magnetic resonance imaging: a case report |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953506/ https://www.ncbi.nlm.nih.gov/pubmed/29770283 http://dx.doi.org/10.7759/cureus.2330 |
work_keys_str_mv | AT elissameidi cardiacamyloidosisdiagnosiswithmagneticresonanceimagingacasereport AT elissamalik cardiacamyloidosisdiagnosiswithmagneticresonanceimagingacasereport AT sidiabesma cardiacamyloidosisdiagnosiswithmagneticresonanceimagingacasereport |