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Ripply2 recruits proteasome complex for Tbx6 degradation to define segment border during murine somitogenesis

The metameric structure in vertebrates is based on the periodic formation of somites from the anterior end of the presomitic mesoderm (PSM). The segmentation boundary is defined by the Tbx6 expression domain, whose anterior limit is determined by Tbx6 protein destabilization via Ripply2. However, th...

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Detalles Bibliográficos
Autores principales:	Zhao, Wei, Oginuma, Masayuki, Ajima, Rieko, Kiso, Makoto, Okubo, Akemi, Saga, Yumiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953544/ https://www.ncbi.nlm.nih.gov/pubmed/29761784 http://dx.doi.org/10.7554/eLife.33068

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