Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system

Retinoic acid (RA), a dietary vitamin A metabolite, is crucial in maintaining intestinal homeostasis. RA acts on intestinal leukocytes to modulate their lineage commitment and function. Although the role of RA has been characterized in immune cells, whether intestinal epithelial cells (IECs) rely on...

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Detalles Bibliográficos
Autores principales: Jijon, Humberto B., Suarez-Lopez, Lucia, Diaz, Oscar E., Das, Srustidhar, De Calisto, Jaime, Yaffe, Michael B., Pittet, Mikael J., Mora, J. Rodrigo, Belkaid, Yasmine, Xavier, Ramnik J., Villablanca, Eduardo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953762/
https://www.ncbi.nlm.nih.gov/pubmed/29139475
http://dx.doi.org/10.1038/mi.2017.91

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