Cargando…
Molecular dynamics simulation (MDS) analysis of Vibrio cholerae ToxT virulence factor complexed with docked potential inhibitors
The ToxT transcription factor mediates the transcription of the two major virulence factors in Vibrio cholerae. It has a DNA binding domain made of α4, α5, α6, α7, α8, α9 and α10 helices that is responsible for the transcription of virulence genes. Therefore, it is of interest to screen ToxT against...
Autores principales: | Torktaz, Ibrahim, Najafi, Ali, Golmohamadi, Reza, Hassani, Sorour |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953856/ https://www.ncbi.nlm.nih.gov/pubmed/29785068 http://dx.doi.org/10.6026/97320630014101 |
Ejemplares similares
-
The complexity of ToxT-dependent transcription in Vibrio cholerae
por: Weber, Gregor G., et al.
Publicado: (2011) -
Small-Molecule Inhibitors of toxT Expression in Vibrio cholerae
por: Anthouard, Rebecca, et al.
Publicado: (2013) -
A new class of inhibitors of the AraC family virulence regulator Vibrio cholerae ToxT
por: Woodbrey, Anne K., et al.
Publicado: (2017) -
Expression of Cholera Toxin (CT) and the Toxin Co-Regulated Pilus (TCP) by Variants of ToxT in Vibrio cholerae Strains
por: Lee, Donghyun, et al.
Publicado: (2023) -
1.65 Å resolution structure of the AraC-family transcriptional activator ToxT from Vibrio cholerae
por: Li, Jiaqin, et al.
Publicado: (2016)