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Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
Epigenetics contributes to the pathogenesis of immune-mediated diseases like rheumatoid arthritis (RA). Here we show the first comprehensive epigenomic characterization of RA fibroblast-like synoviocytes (FLS), including histone modifications (H3K27ac, H3K4me1, H3K4me3, H3K36me3, H3K27me3, and H3K9m...
Autores principales: | Ai, Rizi, Laragione, Teresina, Hammaker, Deepa, Boyle, David L., Wildberg, Andre, Maeshima, Keisuke, Palescandolo, Emanuele, Krishna, Vinod, Pocalyko, David, Whitaker, John W., Bai, Yuchen, Nagpal, Sunil, Bachman, Kurtis E., Ainsworth, Richard I., Wang, Mengchi, Ding, Bo, Gulko, Percio S., Wang, Wei, Firestein, Gary S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953939/ https://www.ncbi.nlm.nih.gov/pubmed/29765031 http://dx.doi.org/10.1038/s41467-018-04310-9 |
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