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Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease
Kawasaki disease (KD), which is the leading cause of pediatric heart disease, is characterized by coronary vasculitis and subsequent aneurysm formation. Although intravenous immunoglobulin therapy is effective for reducing aneurysm formation, a certain number of patients are resistant to this therap...
Autores principales: | Nakamura, Jun, Watanabe, Sachiko, Kimura, Hiroaki, Kobayashi, Motoi, Karasawa, Tadayoshi, Kamata, Ryo, Usui-Kawanishi, Fumitake, Sadatomo, Ai, Mizukami, Hiroaki, Nagi-Miura, Noriko, Ohno, Naohito, Kasahara, Tadashi, Minota, Seiji, Takahashi, Masafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953966/ https://www.ncbi.nlm.nih.gov/pubmed/29765083 http://dx.doi.org/10.1038/s41598-018-25856-0 |
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