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Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease

Kawasaki disease (KD), which is the leading cause of pediatric heart disease, is characterized by coronary vasculitis and subsequent aneurysm formation. Although intravenous immunoglobulin therapy is effective for reducing aneurysm formation, a certain number of patients are resistant to this therap...

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Detalles Bibliográficos
Autores principales: Nakamura, Jun, Watanabe, Sachiko, Kimura, Hiroaki, Kobayashi, Motoi, Karasawa, Tadayoshi, Kamata, Ryo, Usui-Kawanishi, Fumitake, Sadatomo, Ai, Mizukami, Hiroaki, Nagi-Miura, Noriko, Ohno, Naohito, Kasahara, Tadashi, Minota, Seiji, Takahashi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953966/
https://www.ncbi.nlm.nih.gov/pubmed/29765083
http://dx.doi.org/10.1038/s41598-018-25856-0

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