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Leveraging model-informed approaches for drug discovery and development in the cardiovascular space

Cardiovascular disease remains a significant global health burden, and development of cardiovascular drugs in the current regulatory environment often demands large and expensive cardiovascular outcome trials. Thus, the use of quantitative pharmacometric approaches which can help enable early Go/No...

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Detalles Bibliográficos
Autores principales: Dockendorf, Marissa F., Vargo, Ryan C., Gheyas, Ferdous, Chain, Anne S. Y., Chatterjee, Manash S., Wenning, Larissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953982/
https://www.ncbi.nlm.nih.gov/pubmed/29353335
http://dx.doi.org/10.1007/s10928-018-9571-3