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Leveraging model-informed approaches for drug discovery and development in the cardiovascular space
Cardiovascular disease remains a significant global health burden, and development of cardiovascular drugs in the current regulatory environment often demands large and expensive cardiovascular outcome trials. Thus, the use of quantitative pharmacometric approaches which can help enable early Go/No...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953982/ https://www.ncbi.nlm.nih.gov/pubmed/29353335 http://dx.doi.org/10.1007/s10928-018-9571-3 |