Cargando…
Leveraging model-informed approaches for drug discovery and development in the cardiovascular space
Cardiovascular disease remains a significant global health burden, and development of cardiovascular drugs in the current regulatory environment often demands large and expensive cardiovascular outcome trials. Thus, the use of quantitative pharmacometric approaches which can help enable early Go/No...
Autores principales: | Dockendorf, Marissa F., Vargo, Ryan C., Gheyas, Ferdous, Chain, Anne S. Y., Chatterjee, Manash S., Wenning, Larissa A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953982/ https://www.ncbi.nlm.nih.gov/pubmed/29353335 http://dx.doi.org/10.1007/s10928-018-9571-3 |
Ejemplares similares
-
Leveraging Digital Health Technologies and Outpatient Sampling in Clinical Drug Development: A Phase I Exploratory Study
por: Dockendorf, Marissa F., et al.
Publicado: (2018) -
Leveraging big data to transform target selection and drug discovery
por: Chen, B, et al.
Publicado: (2016) -
Designing Chimeric
Molecules for Drug Discovery by
Leveraging Chemical Biology
por: Borsari, Chiara, et al.
Publicado: (2020) -
Leveraging off higher plant phylogenetic insights for antiplasmodial drug discovery
por: Moyo, Phanankosi, et al.
Publicado: (2023) -
PDUFA VI: It Is Time to Unleash the Full Potential of Model‐Informed Drug Development
por: Jain, Lokesh, et al.
Publicado: (2018)