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Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice
Hematopoietic stem cells (HSCs) continuously replenish all blood cell types through a series of differentiation steps and repeated cell divisions that involve the generation of lineage-committed progenitors. However, whether cell division in HSCs precedes differentiation is unclear. To this end, we...
Autores principales: | Grinenko, Tatyana, Eugster, Anne, Thielecke, Lars, Ramasz, Beáta, Krüger, Anja, Dietz, Sevina, Glauche, Ingmar, Gerbaulet, Alexander, von Bonin, Malte, Basak, Onur, Clevers, Hans, Chavakis, Triantafyllos, Wielockx, Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954009/ https://www.ncbi.nlm.nih.gov/pubmed/29765026 http://dx.doi.org/10.1038/s41467-018-04188-7 |
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