Cargando…

PCGF5 is required for neural differentiation of embryonic stem cells

Polycomb repressive complex 1 (PRC1) is an important regulator of gene expression and development. PRC1 contains the E3 ligases RING1A/B, which monoubiquitinate lysine 119 at histone H2A (H2AK119ub1), and has been sub-classified into six major complexes based on the presence of a PCGF subunit. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Mingze, Zhou, Xueke, Zhou, Jiajian, Gong, Shixin, Hu, Gongcheng, Li, Jiao, Huang, Kaimeng, Lai, Ping, Shi, Guang, Hutchins, Andrew P., Sun, Hao, Wang, Huating, Yao, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954019/
https://www.ncbi.nlm.nih.gov/pubmed/29765032
http://dx.doi.org/10.1038/s41467-018-03781-0