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Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common cause of age-related dementia leading to severe irreversible cognitive decline and massive neurodegeneration. While therapeutic approaches for managing symptoms are available, AD currently has no cure. AD associates with a progressive decline of the two ma...
Autores principales: | Bustamante, Hianara A., González, Alexis E., Cerda-Troncoso, Cristobal, Shaughnessy, Ronan, Otth, Carola, Soza, Andrea, Burgos, Patricia V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954036/ https://www.ncbi.nlm.nih.gov/pubmed/29867359 http://dx.doi.org/10.3389/fncel.2018.00126 |
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