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cGMP at the centre of attention: emerging strategies for activating the cardioprotective PKG pathway

The nitric oxide (NO)–protein kinase G (PKG) pathway has been known for some time to be an important target for cardioprotection against ischaemia/reperfusion injury and heart failure. While many approaches for reducing infarct size in patients have failed in the past, the advent of novel drugs that...

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Detalles Bibliográficos
Autores principales: Park, Min, Sandner, Peter, Krieg, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954070/
https://www.ncbi.nlm.nih.gov/pubmed/29766323
http://dx.doi.org/10.1007/s00395-018-0679-9