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cGMP at the centre of attention: emerging strategies for activating the cardioprotective PKG pathway
The nitric oxide (NO)–protein kinase G (PKG) pathway has been known for some time to be an important target for cardioprotection against ischaemia/reperfusion injury and heart failure. While many approaches for reducing infarct size in patients have failed in the past, the advent of novel drugs that...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954070/ https://www.ncbi.nlm.nih.gov/pubmed/29766323 http://dx.doi.org/10.1007/s00395-018-0679-9 |