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Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels

Activity of voltage-gated potassium (Kv) channels controls membrane potential, which subsequently regulates cytoplasmic free calcium concentration ([Ca(2+)](cyt)) in pulmonary artery smooth muscle cells (PASMCs). Acute hypoxia inhibits Kv channel function in PASMCs, inducing membrane depolarization...

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Detalles Bibliográficos
Autores principales: Sweeney, Michèle, Yuan, Jason X-J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59541/
https://www.ncbi.nlm.nih.gov/pubmed/11667964
http://dx.doi.org/10.1186/rr11