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Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels
Activity of voltage-gated potassium (Kv) channels controls membrane potential, which subsequently regulates cytoplasmic free calcium concentration ([Ca(2+)](cyt)) in pulmonary artery smooth muscle cells (PASMCs). Acute hypoxia inhibits Kv channel function in PASMCs, inducing membrane depolarization...
Autores principales: | Sweeney, Michèle, Yuan, Jason X-J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59541/ https://www.ncbi.nlm.nih.gov/pubmed/11667964 http://dx.doi.org/10.1186/rr11 |
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