SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition

Macrophages are susceptible to human immunodeficiency virus type 1 (HIV-1) infection despite abundant expression of antiviral proteins. Perhaps the most important antiviral protein is the restriction factor sterile alpha motif domain and histidine/aspartic acid domain-containing protein 1 (SAMHD1)....

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Detalles Bibliográficos
Autores principales: Szaniawski, Matthew A., Spivak, Adam M., Cox, James E., Catrow, Jonathan L., Hanley, Timothy, Williams, Elizabeth S. C. P., Tremblay, Michel J., Bosque, Alberto, Planelles, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954222/
https://www.ncbi.nlm.nih.gov/pubmed/29764952
http://dx.doi.org/10.1128/mBio.00819-18

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