Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections

Viral pneumonias cause profound worldwide morbidity, necessitating novel strategies to prevent and treat these potentially lethal infections. Stimulation of intrinsic lung defenses via inhalation of synergistically acting Toll-like receptor (TLR) agonists protects mice broadly against pneumonia, inc...

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Detalles Bibliográficos
Autores principales: Kirkpatrick, Carson T., Wang, Yongxing, Leiva Juarez, Miguel M., Shivshankar, Pooja, Pantaleón García, Jezreel, Plumer, Alexandria K., Kulkarni, Vikram V., Ware, Hayden H., Gulraiz, Fahad, Chavez Cavasos, Miguel A., Martinez Zayes, Gabriela, Wali, Shradha, Rice, Andrew P., Liu, Hongbing, Tour, James M., Sikkema, William K. A., Cruz Solbes, Ana S., Youker, Keith A., Tuvim, Michael J., Dickey, Burton F., Evans, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954225/
https://www.ncbi.nlm.nih.gov/pubmed/29764948
http://dx.doi.org/10.1128/mBio.00696-18

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