Physiological concept of hapten-carrier adduct vis-a-vis Garavisha

The human body defends itself from harmful agents such as microorganisms present in the environment, which otherwise damage the individual’s health. This defensive mechanism is the immune response mediated by the activation of T-cell and B-cell antibody production. The body recognizes and destroys these antigenic harmful agents. The defensive response is altered sometimes in the presence of allergens, causing hypersensitive reactions. The allergens are antigens. The hapten-carrier adduct often behaves as an allergen-producing hypersensitivity with a manifestation of sign and symptoms those are at times lethal. Garavisha is an artificial type of poison formed by combination of two nonpoisonous substances as depicted in the treaties of Ayurveda. It has identical characteristics to that of hapten-carrier adduct. In the present article, Garavisha is substantiated with conceptual reference to hapten-carrier adduct and hypersensitivity.