Identification of usual interstitial pneumonia pattern using RNA-Seq and machine learning: challenges and solutions

BACKGROUND: We developed a classifier using RNA sequencing data that identifies the usual interstitial pneumonia (UIP) pattern for the diagnosis of idiopathic pulmonary fibrosis. We addressed significant challenges, including limited sample size, biological and technical sample heterogeneity, and re...

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Detalles Bibliográficos
Autores principales: Choi, Yoonha, Liu, Tiffany Ting, Pankratz, Daniel G., Colby, Thomas V., Barth, Neil M., Lynch, David A., Walsh, P. Sean, Raghu, Ganesh, Kennedy, Giulia C., Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954282/
https://www.ncbi.nlm.nih.gov/pubmed/29764379
http://dx.doi.org/10.1186/s12864-018-4467-6

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