p53 isoforms regulate premature aging in human cells

Cellular senescence is a hallmark of normal aging and aging-related syndromes, including the premature aging disorder Hutchinson-Gilford Progeria Syndrome (HGPS), a rare genetic disorder caused by a single mutation in the LMNA gene that results in the constitutive expression of a truncated splicing...

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Detalles Bibliográficos
Autores principales: von Muhlinen, Natalia, Horikawa, Izumi, Alam, Fatima, Isogaya, Kazunobu, Lissa, Delphine, Vojtesek, Borek, Lane, David P, Harris, Curtis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954431/
https://www.ncbi.nlm.nih.gov/pubmed/29429991
http://dx.doi.org/10.1038/s41388-017-0101-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954431/
https://www.ncbi.nlm.nih.gov/pubmed/29429991
http://dx.doi.org/10.1038/s41388-017-0101-3

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