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Talimogene Laherparepvec combined with anti-PD-1 based immunotherapy for unresectable stage III-IV melanoma: a case series
BACKGROUND: Talimogene Laherparepvec (T-VEC) is an oncolytic virus approved as an intratumoral therapy for treating unresectable stage IIIB-IV metastatic melanoma. The mechanisms of action for T-VEC and checkpoint inhibitor are highly complementary. Recent studies have shown that combining checkpoin...
Autores principales: | Sun, Lillian, Funchain, Pauline, Song, Jung Min, Rayman, Patricia, Tannenbaum, Charles, Ko, Jennifer, Mcnamara, Michael, Marcela Diaz-Montero, C., Gastman, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954455/ https://www.ncbi.nlm.nih.gov/pubmed/29764498 http://dx.doi.org/10.1186/s40425-018-0337-7 |
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