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Talimogene Laherparepvec combined with anti-PD-1 based immunotherapy for unresectable stage III-IV melanoma: a case series

BACKGROUND: Talimogene Laherparepvec (T-VEC) is an oncolytic virus approved as an intratumoral therapy for treating unresectable stage IIIB-IV metastatic melanoma. The mechanisms of action for T-VEC and checkpoint inhibitor are highly complementary. Recent studies have shown that combining checkpoin...

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Detalles Bibliográficos
Autores principales: Sun, Lillian, Funchain, Pauline, Song, Jung Min, Rayman, Patricia, Tannenbaum, Charles, Ko, Jennifer, Mcnamara, Michael, Marcela Diaz-Montero, C., Gastman, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954455/
https://www.ncbi.nlm.nih.gov/pubmed/29764498
http://dx.doi.org/10.1186/s40425-018-0337-7

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