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Somatostatin receptor based hybrid imaging in sarcoidosis

Several diagnostic imaging methodologies are available for the clinical evaluation of sarcoidosis, but all have their limitations. FDG PET/CT is frequently used, but this technique does not provide optimal results in all cases. Novel radiopharmaceuticals aimed at other disease targets may be helpful...

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Detalles Bibliográficos
Autores principales: Slart, Riemer H. J. A., Koopmans, Klaas-Pieter, van Geel, Peter Paul, Kramer, Henk, Groen, Harry J. M., Gan, C. Tji-Joong, Prakken, Niek H. J., Glaudemans, Andor W. J. M., Nossent, George D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954781/
https://www.ncbi.nlm.nih.gov/pubmed/29782604
http://dx.doi.org/10.1186/s41824-017-0014-y
Descripción
Sumario:Several diagnostic imaging methodologies are available for the clinical evaluation of sarcoidosis, but all have their limitations. FDG PET/CT is frequently used, but this technique does not provide optimal results in all cases. Novel radiopharmaceuticals aimed at other disease targets may be helpful, particularly in cardiac sarcoidosis when FDG PET/CT has a low diagnostic accuracy, due to difficulties in preparing the patients who should use a specific diet combined with prolonged fasting. (68)Ga-labeled somatostatin based receptor hybrid imaging is a potential alternative to FDG PET/CT. This short communication provides a rapid overview of initial findings concerning the application of (68)Ga-labeled somatostatin based receptor hybrid imaging in the diagnosis of (cardiac) sarcoidosis activity.