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Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics
Mycophenolic acid (MPA), is the active form of the ester prodrug mycophenolate mofetil (MMF). MMF is an FDA approved immunosuppressive drug that has been successfully used in systemic therapy in combination with other agents for the prevention of acute rejection (AR) following solid organ transplant...
Autores principales: | Feturi, Firuz G., Weinstock, Matthias, Zhao, Wenchen, Zhang, Wei, Schnider, Jonas T., Erbas, Vasil E., Oksuz, Sinan, Plock, Jan A., Rohan, Lisa, Spiess, Alexander M., Ferreira, Lydia M., Solari, Mario G., Venkataramanan, Raman, Gorantla, Vijay S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954844/ https://www.ncbi.nlm.nih.gov/pubmed/29868602 http://dx.doi.org/10.3389/fsurg.2018.00020 |
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