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Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics

Accumulating evidences indicate that many tumors rely on subpopulations of cancer stem cells (CSCs) with the ability to propagate malignant clones indefinitely and to produce an overt cancer. Of importance, CSCs seem to be more resistant to the conventional cytotoxic treatments, driving tumor growth...

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Detalles Bibliográficos
Autores principales: Poli, Vittoria, Fagnocchi, Luca, Zippo, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954911/
https://www.ncbi.nlm.nih.gov/pubmed/29853913
http://dx.doi.org/10.1155/2018/4598195

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