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Factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from Xinjiang, China

PURPOSE: The analysis of factors affecting the nonadherence to antihypertensive medications is important in the control of blood pressure among patients with hypertension. The purpose of this study was to assess the relationship between factors and medication adherence in Xinjiang community-managed...

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Autores principales: Zhang, Yuji, Li, Xiaoju, Mao, Lu, Zhang, Mei, Li, Ke, Zheng, Yinxia, Cui, Wangfei, Yin, Hongpo, He, Yanli, Jing, Mingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955046/
https://www.ncbi.nlm.nih.gov/pubmed/29785095
http://dx.doi.org/10.2147/PPA.S158662
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author Zhang, Yuji
Li, Xiaoju
Mao, Lu
Zhang, Mei
Li, Ke
Zheng, Yinxia
Cui, Wangfei
Yin, Hongpo
He, Yanli
Jing, Mingxia
author_facet Zhang, Yuji
Li, Xiaoju
Mao, Lu
Zhang, Mei
Li, Ke
Zheng, Yinxia
Cui, Wangfei
Yin, Hongpo
He, Yanli
Jing, Mingxia
author_sort Zhang, Yuji
collection PubMed
description PURPOSE: The analysis of factors affecting the nonadherence to antihypertensive medications is important in the control of blood pressure among patients with hypertension. The purpose of this study was to assess the relationship between factors and medication adherence in Xinjiang community-managed patients with hypertension based on the principal component analysis. PATIENTS AND METHODS: A total of 1,916 community-managed patients with hypertension, selected randomly through a multi-stage sampling, participated in the survey. Self-designed questionnaires were used to classify the participants as either adherent or nonadherent to their medication regimen. A principal component analysis was used in order to eliminate the correlation between factors. Factors related to nonadherence were analyzed by using a χ(2)-test and a binary logistic regression model. RESULTS: This study extracted nine common factors, with a cumulative variance contribution rate of 63.6%. Further analysis revealed that the following variables were significantly related to nonadherence: severity of disease, community management, diabetes, and taking traditional medications. CONCLUSION: Community management plays an important role in improving the patients’ medication-taking behavior. Regular medication regimen instruction and better community management services through community-level have the potential to reduce nonadherence. Mild hypertensive patients should be monitored by community health care providers.
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spelling pubmed-59550462018-05-21 Factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from Xinjiang, China Zhang, Yuji Li, Xiaoju Mao, Lu Zhang, Mei Li, Ke Zheng, Yinxia Cui, Wangfei Yin, Hongpo He, Yanli Jing, Mingxia Patient Prefer Adherence Original Research PURPOSE: The analysis of factors affecting the nonadherence to antihypertensive medications is important in the control of blood pressure among patients with hypertension. The purpose of this study was to assess the relationship between factors and medication adherence in Xinjiang community-managed patients with hypertension based on the principal component analysis. PATIENTS AND METHODS: A total of 1,916 community-managed patients with hypertension, selected randomly through a multi-stage sampling, participated in the survey. Self-designed questionnaires were used to classify the participants as either adherent or nonadherent to their medication regimen. A principal component analysis was used in order to eliminate the correlation between factors. Factors related to nonadherence were analyzed by using a χ(2)-test and a binary logistic regression model. RESULTS: This study extracted nine common factors, with a cumulative variance contribution rate of 63.6%. Further analysis revealed that the following variables were significantly related to nonadherence: severity of disease, community management, diabetes, and taking traditional medications. CONCLUSION: Community management plays an important role in improving the patients’ medication-taking behavior. Regular medication regimen instruction and better community management services through community-level have the potential to reduce nonadherence. Mild hypertensive patients should be monitored by community health care providers. Dove Medical Press 2018-05-11 /pmc/articles/PMC5955046/ /pubmed/29785095 http://dx.doi.org/10.2147/PPA.S158662 Text en © 2018 Zhang et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Zhang, Yuji
Li, Xiaoju
Mao, Lu
Zhang, Mei
Li, Ke
Zheng, Yinxia
Cui, Wangfei
Yin, Hongpo
He, Yanli
Jing, Mingxia
Factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from Xinjiang, China
title Factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from Xinjiang, China
title_full Factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from Xinjiang, China
title_fullStr Factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from Xinjiang, China
title_full_unstemmed Factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from Xinjiang, China
title_short Factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from Xinjiang, China
title_sort factors affecting medication adherence in community-managed patients with hypertension based on the principal component analysis: evidence from xinjiang, china
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955046/
https://www.ncbi.nlm.nih.gov/pubmed/29785095
http://dx.doi.org/10.2147/PPA.S158662
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