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Bufalin inhibits gastric cancer invasion and metastasis by down-regulating Wnt/ASCL2 expression
Achaete-scute-like 2 (ASCL2) is a transcription factor containing a basic helix-loop-helix (bHLH) domain and is a downstream target of Wnt signaling in intestinal stem cells. Bufalin is the primary active ingredient in Chan Su, a traditional Chinese medicine obtained from the skin and parotid venom...
Autores principales: | Wang, Jie, Cai, Han, Xia, Yue, Wang, Shiying, Xing, Likai, Chen, Chao, Zhang, Yong, Xu, Jie, Yin, Peihao, Jiang, Yiming, Zhao, Ronghua, Zuo, Qingshong, Chen, Teng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955089/ https://www.ncbi.nlm.nih.gov/pubmed/29805736 http://dx.doi.org/10.18632/oncotarget.24157 |
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