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Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients

Chronic Myeloid Leukemia (CML) is a stem cell disease sustained by a rare population of quiescent cells which are to some extent resistant to tyrosine kinase inhibitors (TKIs). BCR-ABL oncogene activates multiple cross-talking signal transduction pathways (STP), such as RAS/MEK/ERK, PI3K/Akt, Wnt an...

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Detalles Bibliográficos
Autores principales: Ricciardi, Maria Rosaria, Salvestrini, Valentina, Licchetta, Roberto, Mirabilii, Simone, Forcato, Mattia, Gugliotta, Gabriele, Salati, Simona, Castagnetti, Fausto, Rosti, Gianantonio, Breccia, Massimo, Alimena, Giuliana, Manfredini, Rossella, Bicciato, Silvio, Lemoli, Roberto Massimo, Tafuri, Agostino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955129/
https://www.ncbi.nlm.nih.gov/pubmed/29774100
http://dx.doi.org/10.18632/oncotarget.24938