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A targeted transforming growth factor-beta (TGF-β) blocker, TTB, inhibits tumor growth and metastasis

Transforming growth factor beta (TGF-β) promotes cancer growth in late stage cancers. To inhibit the TGF-β pathway, we investigated a tumor-targeting TGF-β receptor blocker, TTB, and its role in tumor progress. The targeted TTB comprised of the extracellular domain of the TGF-β receptor II, the endo...

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Detalles Bibliográficos
Autores principales:	Zhou, Changhua, Li, Jing, Lin, Limin, Shu, Rui, Dong, Bin, Cao, Donglin, Li, Qing, Wang, Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955403/ https://www.ncbi.nlm.nih.gov/pubmed/29796175 http://dx.doi.org/10.18632/oncotarget.24562

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