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Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma

Sunitinib is a standard molecular-targeted drug used as a first-line treatment for metastatic clear cell renal cell carcinoma (ccRCC); however, resistance to sunitinib has become a major problem in medical practice. Recently, bromodomain containing 4 (BRD4), a member of the bromodomain family protei...

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Detalles Bibliográficos
Autores principales: Sakaguchi, Takashi, Yoshino, Hirofumi, Sugita, Satoshi, Miyamoto, Kazutaka, Yonemori, Masaya, Osako, Yoichi, Meguro-Horike, Makiko, Horike, Shin-Ichi, Nakagawa, Masayuki, Enokida, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955408/
https://www.ncbi.nlm.nih.gov/pubmed/29796168
http://dx.doi.org/10.18632/oncotarget.25190

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