Cancer stem cells of hepatocellular carcinoma

Hepatocellular carcinoma is a malignant tumor arising from hepatocytes. The hepatocellular carcinoma is dictated by a subset of cells with stem cell-like features. These cells are apoptosis-resistant and have particular biomarkers, which serve as seeds in different stages of tumorigenesis including...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Kewei, Sun, Dianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955417/
https://www.ncbi.nlm.nih.gov/pubmed/29796190
http://dx.doi.org/10.18632/oncotarget.24623
_version_ 1783323707770404864
author Wang, Kewei
Sun, Dianjun
author_facet Wang, Kewei
Sun, Dianjun
author_sort Wang, Kewei
collection PubMed
description Hepatocellular carcinoma is a malignant tumor arising from hepatocytes. The hepatocellular carcinoma is dictated by a subset of cells with stem cell-like features. These cells are apoptosis-resistant and have particular biomarkers, which serve as seeds in different stages of tumorigenesis including initiation, progression, metastasis, and relapse of hepatocellular carcinoma. Signaling pathways of cancer stem cells are novel targets for the radical intervention of hepatocellular carcinoma.
format Online
Article
Text
id pubmed-5955417
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Impact Journals LLC
record_format MEDLINE/PubMed
spelling pubmed-59554172018-05-24 Cancer stem cells of hepatocellular carcinoma Wang, Kewei Sun, Dianjun Oncotarget Review Hepatocellular carcinoma is a malignant tumor arising from hepatocytes. The hepatocellular carcinoma is dictated by a subset of cells with stem cell-like features. These cells are apoptosis-resistant and have particular biomarkers, which serve as seeds in different stages of tumorigenesis including initiation, progression, metastasis, and relapse of hepatocellular carcinoma. Signaling pathways of cancer stem cells are novel targets for the radical intervention of hepatocellular carcinoma. Impact Journals LLC 2018-05-01 /pmc/articles/PMC5955417/ /pubmed/29796190 http://dx.doi.org/10.18632/oncotarget.24623 Text en Copyright: © 2018 Wang et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Review
Wang, Kewei
Sun, Dianjun
Cancer stem cells of hepatocellular carcinoma
title Cancer stem cells of hepatocellular carcinoma
title_full Cancer stem cells of hepatocellular carcinoma
title_fullStr Cancer stem cells of hepatocellular carcinoma
title_full_unstemmed Cancer stem cells of hepatocellular carcinoma
title_short Cancer stem cells of hepatocellular carcinoma
title_sort cancer stem cells of hepatocellular carcinoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955417/
https://www.ncbi.nlm.nih.gov/pubmed/29796190
http://dx.doi.org/10.18632/oncotarget.24623
work_keys_str_mv AT wangkewei cancerstemcellsofhepatocellularcarcinoma
AT sundianjun cancerstemcellsofhepatocellularcarcinoma

Ejemplares similares