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miR-34a, miR-424 and miR-513 inhibit MMSET expression to repress endometrial cancer cell invasion and sphere formation

Although the oncogene MMSET (also known as NSD2 or WHSC1) has an essential role in malignancies, its impact on human endometrial cancer (EC) metastasis and the molecular mechanism of MMSET regulation are largely unknown. We report that MMSET was markedly upregulated in EC cell lines and EC tissues,...

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Detalles Bibliográficos
Autores principales: Dong, Peixin, Xiong, Ying, Yue, Junming, Hanley, Sharon J.B., Watari, Hidemichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955424/
https://www.ncbi.nlm.nih.gov/pubmed/29796186
http://dx.doi.org/10.18632/oncotarget.25298