MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive behavior of medulloblastoma cells

Local tissue infiltration of Medulloblastoma (MB) tumor cells precedes metastatic disease but little is still known about intrinsic regulation of migration and invasion in these cells. We found that MAP4K4, a pro-migratory Ser/Thr kinase, is overexpressed in 30% of primary MB tumors and that increas...

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Detalles Bibliográficos
Autores principales: Tripolitsioti, Dimitra, Kumar, Karthiga Santhana, Neve, Anuja, Migliavacca, Jessica, Capdeville, Charles, Rushing, Elisabeth J., Ma, Min, Kijima, Noriyuki, Sharma, Ashish, Pruschy, Martin, McComb, Scott, Taylor, Michael D., Grotzer, Michael A., Baumgartner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955425/
https://www.ncbi.nlm.nih.gov/pubmed/29796184
http://dx.doi.org/10.18632/oncotarget.25294

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