PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target

Rotavirus infection is a major cause of severe dehydrating diarrhea in infants younger than 5 y old and in particular cases of immunocompromised patients irrespective to the age of the patients. Although vaccines have been developed, antiviral therapy is an important complement that cannot be substi...

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Detalles Bibliográficos
Autores principales: Yin, Yuebang, Dang, Wen, Zhou, Xinying, Xu, Lei, Wang, Wenshi, Cao, Wanlu, Chen, Sunrui, Su, Junhong, Cai, Xuepeng, Xiao, Shaobo, Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955461/
https://www.ncbi.nlm.nih.gov/pubmed/28475412
http://dx.doi.org/10.1080/21505594.2017.1326443

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